Exam format
- One day, up to 8 hours.
- Seven 60-minute blocks, up to 40 questions per block, ~280 questions total.
- 45 minutes of break time plus a 15-minute tutorial that can be skipped to add to break.
- Delivered at Prometric centers worldwide.
Content areas
Step 1 tests integrated basic and clinical sciences, weighted toward:
- Pathology and pathophysiology
- Pharmacology
- Physiology
- Microbiology and immunology
- Biochemistry and molecular biology
- Behavioral sciences, biostatistics, and ethics
Preparation timeline for Caribbean students
- Longitudinal (semesters 1–4): integrate First Aid annotations and UWorld tutor-mode questions with course work.
- Comprehensive Basic Science Exam (CBSE): most schools require a CBSE benchmark before releasing students to dedicated study.
- Dedicated study (6–10 weeks): full UWorld pass, First Aid review, targeted weak-area work, and 3–4 NBME/UWSA self-assessments.
- Sit exam: typical readiness signal is consistent NBME predicted scores above the passing standard with a safety margin.
What "passing" actually means for your application
A Step 1 pass unlocks US clinical rotations and is required for ECFMG Certification, but it no longer helps you stand out in residency screening. Programs now rely on Step 2 CK, clinical performance, US letters of recommendation, and audition rotations to differentiate applicants. Treat Step 1 as a gate to clear efficiently - then focus energy on Step 2 CK and rotations.
If you fail Step 1
Failure delays clinical rotations and requires a documented remediation plan. Most schools require additional review time and a passing NBME predictor before allowing a retake. Multiple failures compound into ERAS red flags - some programs filter on any Step failure. If you are struggling in basic sciences, address it before scheduling Step 1 rather than after.
